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El blog de biotek: La historia de la Viagra: la industria farmaceútica, un negocio a cara o cruz

El blog de biotek

lunes, diciembre 11, 2006

La historia de la Viagra: la industria farmaceútica, un negocio a cara o cruz


La industria farmaceútica se caracteriza por ser un negocio totalmente imprevisible, en el que un golpe de buena fortuna puede distinguir el éxito del fracaso. Pero lo peor es que la distancia entre el éxito y el fracaso, en un sólo producto, puede significar dejar de vender ¡mil millones de euros! ¡¡cada año!! La historia del descubrimiento de la Viagra ilustra esto de forma inmejorable, pues es la historia de un fracaso que se convirtió en un éxito empresarial sin precedentes, por un golpe del destino. La disfunción eréctil afecta al 10 por ciento de los hombres. Pero este porcentaje pasa a ser del 52 por ciento en los hombres de 40 a 70 años. La Viagra no es la única pero sí fue la primera droga oral contra la impotencia. Actualmente vende casi dos mil millones al año de euros, con unos márgenes de beneficios cercanos al 90%. La historia del descubrimiento es interesante porque ilustra como un golpe de suerte puede cambiar los beneficios de una empresa. Es algo que no pasa en ninguna otra actividad empresarial con esta magnitud, con esa sensación de capricho del destino. Aunque por supuesto hay que andar listo para detectar las oportunidades.
Todo comenzó en 1985, cuando Simon Campbell y David Roberts, ambos químicos en Pfizer, emprendieron la tarea de encontrar un compuesto contra la hipertensión, descubriendo el sildenafil. Pfizer comenzó ensayos clínicos de la fase I del sildenafil en voluntarios sanos, sin historial de enfermedad cardíaca coronaria, seis años después, en julio de 1991. El año siguiente, dos cosas sucedieron en paralelo, cambiando la dirección de la investigación. Al entrar en fase II, la droga no satisfizo las expectativas del equipo en términos de actividad en los pacientes que tenían enfermedad cardíaca coronaria severa. Sin embargo, durante un estudio en el que se aumentó la dosis al máximo, para observar cuánta droga se podría dar a los voluntarios sin incurrir en efectos secundarios, los voluntarios manifestaron efectos secundarios, incluyendo dolor de cabeza, indigestión, problemas visuales, dolores musculares, así como un cambio en la función eréctil. Un efecto secundario curioso… Para el equipo del descubrimiento este cambio en la función eréctil era un fenómeno interesante. Como la droga no parecía prometedora para tratar a pacientes con enfermedad coronaria, el equipo discutió la posibilidad de usar el sildenafil como droga terapéutica contra la impotencia. En mayo de 1994 Pfizer comenzó el primer ensayo de la fase II del sildenafil en los hombres que sufrían de impotencia. El resto es historia. Una historia de éxito empresarial y farmaceútico. Por cierto, la sustancia activa es blanca, el color azul es Marketing. Si no la has probado, es impresionante, te lo aseguro, yo siempre tengo alguna a mano por si acaso ;-).

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338 comentarios:

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Blogger PROFESOR COCCA ha dicho...

Los excesos de la Industria Farmacéutica : por Eduardo Marcelo Cocca *
Acostumbrados desde siempre a un manejo discrecional e inconsulto de sus políticas, salvo con sus dos mayores cámaras y algunas pequeñas entidades del sector viven en una burbuja ajenos a los padecerse de la nación que sea.
Los costos de los medicamentos, en particular su materia prima habitualmente, salvo excepciones, cuesta mas su empaque que el producto en si, las ganancias desde siempre, no se trata de ninguna novedad rondan entre el dos mil y dos mil quinientos por ciento, este escándalo que no es ni fue nunca ajeno a las autoridades de turno no termina aca, a esto debemos sumarle lo que se denomina aumentos ponderados de precios, que es esto, todos los laboratorios farmacéuticos tienen en sus listas de precios productos que valen centavos o monedas y que por supuesto siempre están en falta en las droguerías y laboratorios productores, no son productos que se tienen en lista para en algún momento relanzar y vender, al contrario, sirven para cuando se obtiene un aumento acordado por el gobierno, estos no se modifican en su valor al publico,total no existen, aca no se pierde nada, ese porcentaje que le corresponde al producto fantasma, es sumado al producto de mas venta de la empresa de forma tal que si a tal producto le autorizaron cuarenta por ciento de aumento, el aumento real, pasa a ser del ochenta por ciento.
Una de mis actividades es ser Profesor Universitario, asignatura Ejercicio y Administracion Farmaceutica, carrera de Farmacia, ( entre otras ), como trabajo practico en clase con mis mas de cincuenta ( 50 ) alumnos, quisimos sacar el costo real, de un producto con mas de 40 años en el mercado, un descongestivo nasal en gotas, sustancia basica, nafazolina, averiguamos y diferentes cursantes que trabajan en farmacias que hacen recetas magistrales consultaron al mas importante droguero de sustancias diversas para toda la actividad farmaceutica, cual fue la tamaña sorpresa para todos, que el costo del descongestivo, por unidad es de 0,03 centavos y el precio de venta al publico es de 11,25 pesos, esto nos da un margen de ganancia del 37.500 POR CIENTO, este margen seguramente es superior si la nafazolina se compra directamente en India o en China, los dos paises que proveen materias primas a practicamente toda la industria farmaceutica.
Estos porcentajes de ganancia, lamentablemente son validos para practicamente todo el espectro de especificos farmaceuticos.
Esto no es un exceso, es un escandalo y alguien debera mas que urgente hacer algo y desgraciadamente tanta inequidad no acaba aqui, ahora tenemos desabastecimiento de medicamentos.

Todos los funcionarios, todos los gobiernos, siempre fueron concientes, de este despojo a la totalidad de la población de la Nación.
Ni hablemos de los míseros porcentajes, que le permiten ganar a los farmacéuticos, convirtiéndolos en casi empleados gratis de los laboratorios farmacéuticos al igual que los médicos.
El Estado Nacional, tiene y sabe de las variadas formas que hay para revertir esta situación.
Asimismo lamento, el silencio, de los colegio de farmacéuticos, colegios médicos, entidades supuestamente defensoras de los derechos del consumidor, me pregunto a todos nosotros, nos representa alguien.
Esperemos que algún día, la grandeza que anida en el corazón de todo argentino bien nacido aflore y solucione estas otras cuestiones de tanta o mas gravedad.
Datos del autor del texto
*(*)Procurador, Abogado y Profesor Universitario.Docente con el cargo de Jefe de Trabajos Prácticos, durante 24 meses, en la Facultad de Derecho de la Universidad de Lomas de Zamora, en la cátedra Realidad Social Latinoamericana y Derecho. Docente en la Facultad de Derecho, de la Universidad Maimonides, en la cátedra de Derecho Empresarial ( orientación Derecho Constitucional). Docente a cargo de las cátedras „Economía y Legislación „ y Ejercicio y Administración Farmacéutica‰ en la Universidad Kennedy. Docente de Legislación y Práctica Aduanera en la Universidad Kennedy. Docente de Derecho Administrativo en la Universidad Kennedy. Profesor Adjunto, de Economia Politica, en la carrera de Abogacia de la Universidad Abierta Interamericana.Profesor en la Carrera de Periodismo de la asignaturas Aspectos Legales y Eticos del Periodismo, en la Universidad Kennedy. Profesor de Aspectos Legales de la Informatica, de la Lic. en Sistemas Informaticos, de la Universidad Kennedy. Profesor Universitario , egresado como tal, del Profesorado Universitario de la Universidad Maimonides. Colegiado, matriculado en el Colegio Publico de Abogados de la Capital Federal (Tomo 74; Folio 0976) y en la Cámara Federal De Apelaciones de la Plata (Corte Suprema de Justicia de la Nación), (Tomo 201; Folio 795 )
profcocca@gmail.com

Este es un e-mail legal, libre de virus y contiene informacion que consideramos de su interés.
De acuerdo con la nueva Ley argentina Nº 26032 la libre distribución este email está autorizada
por tratarse de propósitos de información, sin embargo, si le hemos causado alguna molestia por el mismo,
le rogamos acepte nuestras disculpas y nos envie un mail a
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SERVICIO DE INTERNET


Ley 26.032


Establécese que la búsqueda, recepción y difusión de información e ideas por medio del servicio de Internet se considera comprendida dentro de la garantía constitucional que ampara la libertad de expresión.


Sancionada: Mayo 18 de 2005

Promulgada de Hecho: Junio 16 de 2005


El Senado y Cámara de Diputados de la Nación Argentina reunidos en Congreso, etc.

sancionan con fuerza de Ley:

ARTICULO 1°

— La búsqueda, recepción y difusión de información e ideas de toda índole, a través del servicio de Internet, se considera comprendido dentro de la garantía constitucional que ampara la libertad de expresión.

ARTICULO 2°

— La presente ley comenzará a regir a partir del día siguiente al de su publicación en el Boletín Oficial.

ARTICULO 3°

— Comuníquese al Poder Ejecutivo.


—REGISTRADA BAJO EL N° 26.032—


DADA EN LA SALA DE SESIONES DEL CONGRESO ARGENTINO, EN BUENOS AIRES, A LOS DIECIOCHO DIAS DEL MES DE MAYO DEL AÑO DOS MIL CINCO.


EDUARDO O. CAMAÑO. — MARCELO A. GUINLE. — Eduardo D. Rollano. — Juan Estrada.

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La impotencia o disfunción eréctil es una condición que estan padeciendo cientos de hombre de todas las edades en Puerto Rico y en los Estados Unidos.

La ciencia medica conoce que. los hombres que sufren diabetes tipo 2 y que tienen problemas para mantener una erección podrían estar en riesgo de desarrollar problemas cardíacos, según afirman los médicos especialistas.

La disfunción eréctil podría ser una verdadera advertencia para hombres con problemas del corazón o diabetes, con consecuencias tan graves como un infarto e incluso muerte.

La causa, afirman los investigadores de la Universidad China de Hong Kong, pueden ser los daños en los vasos sanguíneos causados por los altos niveles de azúcar en la sangre.

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Algunos medicamentos para problemas para la hipertension resultaron altamente efectivos para la irrigación sanguínea en el area peneal, pero con severos y fuertes efectos secundarios en aquellos hombres que tienen condiciones concomitantes como la diabetes tipo 2.

Este es el caso del citrato de sildenafil (viagra), conocido para mantener una erección completa, ya tiene efectos adversos que pueden llevar a un ataque al corazón. Otros efectos secundarios más frecuentes son: dolor de cabeza, enrojecimiento de la cara, náuseas, congestión nasal, mareos, visión anormal o borrosa, sensibilidad a la luz, dolor en la vejiga y al orinar, orina oscura o con restos de sangre.

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Esta terapia es absolutamente segura y no sentirá ninguno de los efectos secundarios observados en los medicamentos químico-farmaceuticos. Su salud estará protegida. Debemos recordar que la impotencia o disfunción eréctil puede ser causada por una gran variedad de condiciones, tanto emocionales como fisiológicas.

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